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These findings demonstrate species differences in complement-mediated nanoparticle recognition and uptake by leukocytes, and further show that human hemocompatibility could be improved by inhibitors of complement. The residual uptake of cross-linked nanoparticles was completely blocked by EDTA. Remarkably, the cross-linked particles did not show a decrease in C3 opsonization in human serum, but showed a significant decrease (over 60%) of the uptake by human. Pasport kachestva obrazec rb 2. • Schilling, P.

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